Chris Hale faces a dilemma, he must hire Capt. Dan Brady as a trail scout or lose his government mail contract, or love Flint, his right-hand man.
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Kitty Allbright is a nurse who joins the wagon train. She soon becomes concerned about the people's poor sanitation habits.
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Flint is scouting and meets an all female wagon train. Maud is the wagonmistress and she cannot be convinced that it isn't safe for them to cross Indian country alone. Flint tries to convinc...
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Selena Hartnell is a bounty hunter looking for a murderer on the run.
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Hale rescues Clementine Jones after the citizens of Cinnebar throw her out of town as an undesirable.
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Jenna Douglas appears to have been a victim of a scavenger attack and is adopted by the train. Shortly after she joins, other riders begin to have doubts about her story.
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A deathbed wish, Flint's foster mother sends him to find her son Artie, who Flint has struggled to get along with. When Flint finds him, he's been questionably elected mayor.
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Lord Bruce Saybrook, London millionaire, takes his family out west on a hunting trip hoping to repair his relationships. They learn more about each other than expected.
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Lizabeth Ann Calhoun asks permission to join the train so she can avoid the advances of a young man she claims is in love with her.
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Flint goes undercover to infiltrate an outlaw gang.
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Bettina May leads three generations of her family across the plains. Members of the train become concerned with her over-bearing nature towards her family.
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Charlie's life undergoes an epiphany when he finds an injured buffalo and the animal befriends him. He takes the buffalo, who he calls Clyde, as a pet.
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A man finds a corpse that looks remarkably like himself. He takes on the persona of the dead man only to find he was a living legend of west and had made a lot of enemies along the way.
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A young man is found wounded along the trail, after claiming to have been attacked by Indians and left for dead, but perhaps there is more to his story.
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Duke is sent to guide back three wagons that fell behind the train, when he finds them however, he encounters resistance from three men with them.
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An old con man tries to fleece the wagon train by posing as a preacher.
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Flint finds a young boy who witnessed the murder of his father and cannot speak.
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Jeff Hartfield becomes concerned when his sister Jenny begins dating Dallas who threatens to put him in an orphanage at journey's end.
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A judge and his family join the wagon train. Judge Clay has a reputation for cleaning up frontier towns, but his fanatical attention doesn't always draw praise.
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A young lieutenant on his first assignment must face an overbearing, murderous sergeant who is determined to kill two deserters in cold blood.
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The wagon master encounters opposition when he calls a halt to the train due weather. One group needs to push on due to an inheritance in California.
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Flint tries to stop a man who has been taking prisoners and forcing them into slave labor.
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A teacher traveling with the wagon train encounters conflict when he become attracted to the daughter of a preacher who has just joined the train.
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Ousted medicine man predicts future of wagon train passenger. Is it a hoax or real?
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Part of the wagon train splits off to attempt a crossing at dangerous swamp. On the way they hear stories from the local Indians of strange creatures living in the swamp.
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Newlyweds who have joined the wagon train. It isn't long before problems arise when an old friend of Helen shows up.
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Chris Hale is traveling to see his brother Levi, who's about to be released from prison.
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Wagoners find Ben Morrell and his son very antisocial: the two can't even tolerate each other.
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A local hero is declared dead after a payroll robbery.
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A Frenchman arouses strong, and polarized, emotions among the wagoners: men distrust him, women adore him.
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Flint happens to learn the whereabouts of a man he's been hunting for years---to kill.
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Duke's resemblance to gambler Jason Carter makes him the target for a murderer's bullet.
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Bill and Charlie help an old friend, John Turnbull, defend his reservation against local land sharks who look to initiate a range war.
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Duke quits the wagon train to take up a position as Deputy Indian Agent on an Apache reservation under Hiram Winthrope.
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Upon reaching Sacramento, a young wagonmen falls in love with an upper society lady from the train.